Heart
Skin
Pancreas
Brain
Others
Case Study: Perfecting an in vitro model for heart disease
Human cardiomyocytes derived from human induced pluripotent stem cells (hiPSC) are widely used as an in vitro model of heart disease. They represent a promising strategy for disease modelling, drug screening, and cell-based therapeutic applications. But generating hiPSC-derived cardiomyocytes that mimic adult cardiomyocytes is critical to ensure the relevance of the model.
A research team at Sorbonne Université in Paris developed a new protocol for the enrichment of cardiomyocytes and wanted to test the maturation of the resulting cells. Using the Asteria kit and the Cytonaut software, they confirmed at the single-cell resolution that their new protocol generated 90% of cardiomyocytes in the model, and that it favored ventricular cells.
Empowered autonomy
Receive a T-shirt with your single-cell data!
Ask us
