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User Guides

Asteria™ User Guide v1.5 (current)

Here you can download the User Guide of your Asteria™ Single-cell RNA sequencing Kit, in PDF format.

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Brain

June 19, 2023

The temporal balance between self-renewal and differentiation of human neural stem cells requires the Amyloid Precursor Protein.

Neurogenesis in the developing human cerebral cortex occurs at a particularly slow rate owing in par...

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Benchtop Technical Tips

November 30, 2023

The Importance of Fresh Cells for Authentic Transcriptome in Single-cell

In the realm of single-cell sequencing, one of the biggest messages that must not be ignored is ‘gar...

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Other

March 24, 2023

RevGel-seq: instrument-free single-cell RNA sequencing using a reversible hydrogel for cell-specific barcoding

Progress in sample preparation for scRNA‑seq is reported based on RevGel‑seq, a reversible‑hydrogel ...

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User Guides

Cytonaut™ User Guide v1.8 (current)

Here you will find the User Guide for the Cytonaut™ Cloud Software for Single-Cell Data Analysis, in...

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Biological Applications

October 26, 2023

Diving into tiny, tricky, but key tissues at the single-cell level

Dr. Rainer Glauben and Adrian Huck, recipients of one of the Scipio bioscience grant prizes, have sp...

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Tutorials

Asteria™ single-cell RNA-seq kit Tutorial: Coupling to Degelation

This video tutorial showcases individual steps in the protocol for the Asteria single-cell RNA-seq k...

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Biological Applications

October 26, 2023

Cracking the Code of Pancreatic Cancer’s Resilient Stem Cells with scRNA-seq

Pancreatic cancer is one of the deadliest in humans – with a lack of good therapeutic treatments – a...

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Posters

Single-cell RNA Sequencing using Asteria kit showed enrichment in ventricular cardiomyocytes from hiPSc after cell amplification

Scipio bioscience teamed up with Dr. Eric Villard from the Research Unit on Cardiovascular and Met...

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Biological Applications

October 26, 2023

Using single-cell to look into an under-studied area of cancer research

One of the Scipio bioscience grant winners, Assistant Professor Mohamed Omar at Weill Cornell Medici...

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Application Notes
Other

Application note: 35-Day Stopping point

Here you will find the report on our internal study finding no differences by freezing a sample at t...

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Biological Applications

November 24, 2022

Understanding brain evolution using single-cell sequencing

Around 320 million years ago the first animal able to reproduce on land, known as an amniote, emerge...

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Case studies

Case Study: raising the cell size limitations using Cardiomyocytes

To further push back the cell size limitation in single-cell, we processed a cardiomyocyte sample (c...

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Biological Applications

April 8, 2022

Mapping the Cell Types of the Brain

A swathe of 17 linked studies took over an entire issue of Nature last October.

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Posters

Instrument-free single cell RNA sequencing of immune cells in skin inflammatory diseases

In collaboration with the Saint-Louis Hospital, Scipio bioscience has successfully profiled single-c...

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Case studies

Case Study: Alzheimer’s Disease

Scipio bioscience has a long-standing collaboration with Prof. Bassem Hassan, Scientific Director an...

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Single-cell Technologies

February 11, 2022

In vivo Perturb-seq: a Cutting-edge Technique for Studying Gene Perturbations at Single-cell Resolution

Dr. Xin Jin was a key player in the development of in vivo Perturb-seq (published here in 2020) duri...

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Posters

Instrument-Free Single-Cell Resolution of Transcriptome in Mouse Pancreatic Islet Cells

Scipio bioscience collaborates with Bertrand Blondeau and his team at the Centre de Recherches Saint...

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Benchtop Technical Tips

December 16, 2021

Single-cell data integration: plan ahead!

Most publications and presentations will feature the practical details of single-cell experiments an...

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Case studies

Case Study: Oligodendrocytes

Scipio bioscience joined forces with Emmanuelle Huillard and the Genetics and Development of Nervous...

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Benchtop Technical Tips

November 4, 2021

Optimizing tissue and cell dissociation for single-cell preparation

In the early stages of cell dissociation, cells are still intact and alive. This means their transcr...

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Case studies

Case Study: Brain Organoids

Scipio bioscience works with Philippe Ravassard and his lab in the Molecular Pathophysiology of Park...

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Benchtop Technical Tips

July 2, 2021

The impact of methanol fixation on your scRNA-seq dataset

Methanol fixation is among the most widespread technique to preserve a cell sample that cannot be pr...

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Tutorials

Asteria™ single-cell RNA-seq kit Tutorial: Coupling/Gelation

This video tutorial showcases individual steps in the protocol for the Asteria single-cell RNA-seq k...

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Single-cell Technologies

July 10, 2021

Mapping intercellular communication networks with scRNA-seq

Our guest writer Louk Timmer is a Ph.D. candidate in the Van Rooij group at the Hubrecht Institute i...

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Tutorials

Asteria™ single-cell RNA-seq kit Tutorial: Lysis

This video tutorial showcases individual steps in the protocol for the Asteria single-cell RNA-seq k...

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Single-cell Technologies

April 8, 2021

Spatial Isoform Transcriptomics (SiT): spatial landscape of gene expression isoforms in tissue sections

Current high throughput scRNA-seq technologies, including spatial transcriptomics, rely on 3’ short-...

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Tutorials

Asteria™ single-cell RNA-seq kit Tutorial: Degelation

This video tutorial showcases individual steps in the protocol for the Asteria single-cell RNA-seq k...

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Benchtop Technical Tips

January 21, 2021

Collaborating for optimal scRNA-seq bioinformatic analysis

Dr. Marc Beyer agreed to meet us to discuss his journey and the best collaborations he witnessed bet...

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Brochures

Asteria™ and Cytonaut™ Technical Brochure

This digital brochure describes in detail the performances of the Asteria™ single-cell RNA sequencin...

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Benchtop Technical Tips

January 7, 2021

scRNA-seq artifacts from sample preparation

Independently of the scRNA-seq methodology you plan to use, there are genetic artifacts bound to ari...

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Single-cell Technologies

May 6, 2024

To single-cell or not to single-cell: The ins and outs of making the leap

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Certificates

Asteria™ – Certificates of Analysis

Here you will find the Certificate of Analysis (CoA) for the Asteria™ single-cell RNA-seq Kit

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Datasheets

Asteria™ MSDS Safety Datasheet

Here you will find the MSDS - safety datasheet linked to the Asteria™ Single-cell RNA-seq Benchtop k...

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