Application: raising the cell size limitations using Cardiomyocytes as a case study
To further push back the cell size limitation in single-cell, we processed a cardiomyocyte sample (cell size > 30 microns) with the Asteria benchtop scRNA-seq kit. Thanks to the RevGel hydrogel technology, we were able to successfully capture and profile cells whose size prevents them to be used in microfluidic-based technologies.
Application : Human skin
In collaboration with the Saint-Louis Hospital, Scipio bioscience has successfully profiled single-cell skin samples from the dermis and the epidermis. Here we describe the use of the Asteria™ scRNA-seq kit for sample preparation and its Cytonaut™ cloud software for data analysis on human skin samples.
Application: Alzheimer’s Disease
Scipio bioscience has a long-standing collaboration with Prof. Bassem Hassan, Scientific Director and Head of the Brain Development Team at the Paris Brain Institute. Using the RevGel-seq technology patented by Scipio bioscience, we were able to identify new cell subtypes on knock-out models highlighting the role of APP proteins in neuron development.
Certificate of Analysis
Asteria™ – Certificate of Analysis
Here you will find the Certificate of Analysis (CoA) for the Asteria™ single-cell RNA-seq Kit
Asteria™ MSDS Safety Datasheet
Here you will find the MSDS - safety datasheet linked to the Asteria™ Single-cell RNA-seq Benchtop kit product number 001-100.
Cytonaut™ User Guide v1.5 (current)
Here you will find the User Guide for the Cytonaut™ Cloud Software for Single-Cell Data Analysis, in PDF format.
Asteria™ User Guide v1.3 (current)
Here you can download the User Guide of your Asteria™ Single-cell RNA sequencing Kit, in PDF format.
Asteria™ and Cytonaut™ Technical Brochure
This digital brochure describes in detail the performances of the Asteria™ single-cell RNA sequencing kit and the Cytonaut™ cloud-based analysis software. You will find how the Asteria™ kit can help with your single-cell project and its performances on various cell lines.
Application: Pancreatic Islets
Scipio bioscience collaborates with Bertrand Blondeau and his team at the Centre de Recherches Saint-Antoine in Paris to investigate metabolic diseases. In this perspective, samples from the pancreatic islets were successfully profiled with the Asteria single-cell RNA-seq kit.
Scipio bioscience joined forces with Emmanuelle Huillard and the Genetics and Development of Nervous System Tumors team at the Paris Brain Institute to explore glial cell lineage of oligodendrocytes.
Application: Brain Organoids
Scipio bioscience works with Philippe Ravassard and his lab in the Molecular Pathophysiology of Parkinson's disease team at the Paris Brain Institute. The Asteria single-cell RNA-seq kit was used to capture and characterize the heterogeneity of brain organoids.